Histology of the blood, normal and pathological / by P. Ehrlich and A. Lazarus ; edited and translated by W. Myers ; with a preface by G. Sims Woodhead.

Date:
1900
Catalogue details

Licence: In copyright

Credit: Histology of the blood, normal and pathological / by P. Ehrlich and A. Lazarus ; edited and translated by W. Myers ; with a preface by G. Sims Woodhead. Source: Wellcome Collection.

Provider: This material has been provided by the Royal College of Physicians of Edinburgh. The original may be consulted at the Royal College of Physicians of Edinburgh.

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    Quincke has endeavoured to calculate the amount of blood in cases of blood transfusion for therapeutic pur- poses. From the number of red blood corpuscles of the patient before and after blood transfusion, the amount of blood transfused and the number of corpuscles it contains, by a simple mathematical formula the quantity of the blood of the patient can be estimated. But this method is only practicable in special cases and is open to several theoretical errors. First, it depends upon the relative number of red blood corpuscles in the blood; inasmuch as the transfusion of normal blood into normal blood, for example, would produce no alteration in the count. This consideration is enough to shew that this proceeding can only be used in special cases. It has indeed been found that an increase of the red corpuscles per cubic millimetre occurs in persons with a very small number of red corpuscles, who have been injected with normal blood. But it is very hazardous to try to estimate therefrom the volume of the preexisting blood, since the act of transfusion undoubtedly is immediately followed by compensatory currents and alterations in the distribution of the blood. No property of the blood has been so exactly and j frequently tested as the number of red corpuscles I PER CUBIC millimetre OF BLOOD. The convenience of | the counting apparatus, and the apparently absolute | measure of the result have ensured for the methods of enumeration an early clinical application. At the present time the instruments of Thoma-Zeiss or others similarly constructed are generally used; and we may assume that the principle on which they depend and the methods of their use are known. A number of fluids are used to dilute the blood, which on the whole
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