Alzheimer’s Disease is a degenerative disorder of the brain which starts in middle or late life. It mainly affects the frontal and temporal lobes of the brain, where the cortex becomes atrophied. Plaques containing an amyloid-like protein have been found within the cortex on examination.

The earlier symptoms include a progressive loss of recent memory, and gradually increasing confusion of time and space. This image helps to illustrate this, as the sufferer is unable to recognise the most recent photos of friends/relatives in the album, though may still be able to identify those from longer ago.