Serum diagnosis of syphilis and the butyric acid test for syphilis / by Hideyo Noguchi.

Date:
[1911]
Catalogue details

Licence: In copyright

Credit: Serum diagnosis of syphilis and the butyric acid test for syphilis / by Hideyo Noguchi. Source: Wellcome Collection.

Provider: This material has been provided by the Royal College of Physicians of Edinburgh. The original may be consulted at the Royal College of Physicians of Edinburgh.

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    Serum Diagnosis of Syphilis I. SERUM HAEMOLYSIS. The red blood-corpuscles of animals when put in contact with many different substances are so altered that their haemoglobin is set free, the stromata also going into solution, as a rule. This phenomenon of solution is now generally known as hcemolysis. The substances which cause haemolysis are said to be hsemolytic for the blood-corpuscles which they dis- solve. Fresh blood-serum of many animal species is hasmolytic for the erythrocytes of some, but not all, other species. Hsemolysis by serum results from the cooperated (coordinated) action of two distinct serum principles or factors. The first is called amboceptors^ the second complement.^ The latter is always present in all fresh sera: the former, on the other hand, is inconstantly so, frequently being absent from normal blood-serum. If erythrocytes are added to a serum which contains only amboceptor they absorb the am- * Bordet's substance sensibilisatrice, and Metchnikoflfs fixateur. ' Bordet's alexin, and Metchnikoff's cytase.