The leprous diseases of the eye / by O.B. Bull and G.A. Hanson.

  • Bull, O. B. (Ole Bornemann), 1842-1916.
Date:
1873
Catalogue details

Licence: Public Domain Mark

Credit: The leprous diseases of the eye / by O.B. Bull and G.A. Hanson. Source: Wellcome Collection.

Provider: This material has been provided by The Royal College of Surgeons of England. The original may be consulted at The Royal College of Surgeons of England.

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    the Iris, or in the posterior lamellae of the Cornea. We have not always been able to discern macroscopically any obscuration of the corneal substance in front of the deeply situated tuber. The tuber advances with rather sharply defined ontline, like a wedge between the lamellae. Its color is less red, but usually more greyish than that of the superficial tuber. The develop- ment of tubers often takes place sumultaneously in the same eye, both on the surface of the Cornea and in its profound layers. Anatomy. As appears from the clinical description, there exist superficial and profound tubers. The ways by which the tubers grow into the Cornea may be seen from Fig. 11, which is a somewhat schematised delineation composed according to several cuts of the same eye. It may be seen from this deline- ation that the more superficial tubers take their origin from an episcleral formation; and from this they may either advance right under the corneal epithelium, sometimes leaving nearly all the posterior part of the Cornea pellucid, even if the whole surface of the Cornea should be covered by the tuber, or the episcleral tuber is continued along the vessels which extend into the Sclera towards the middle of the thickness of the Cornea, and thence grows like a wedge into the latter, leaving both the anterior and posterior part of the Cornea pellucid. Above the episcleral part of the tuber, the Conjunctiva is usually very easily movable. Only when the tuber grows very rapidly, the submucous tissue becomes also infiltered; so that the epi- thelium rests immediately on the tuber. The most deeply situated tubers proceed from the region round about the Canalis Schlemmii, and advance into the Cornea immediately in front of the Membrana Descemeti; the space between the fibres of the lig. pectinatum iridis are also con- stantly and densely filled with round corpuscles. The obscuration advancing before the tuber, which with the naked eye is most easily seen when the tuber is superficial, and which can always be observed microscopically in cases of deep corneal tubers, corresponds in every way to the leprous Pannus just described. In microscopic preparations it appears, still more distinctly than in clinical examination, that when the tuberous development proceeds from the surface, the layer of round cells which lies immediately before the tuber is thinner than that situated a little nearer to the centre of the Cornea