A study of endometriosis, endosalpingiosis, endocervicosis, and peritoneo-ovarian sclerosis : a clinical and pathologic study / by James Robert Goodall.

  • Goodall, James Robert, 1877-1947.
Date:
1943
Catalogue details

Licence: In copyright

Credit: A study of endometriosis, endosalpingiosis, endocervicosis, and peritoneo-ovarian sclerosis : a clinical and pathologic study / by James Robert Goodall. Source: Wellcome Collection.

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    In 1921 Sampson first elaborated his “spill” and “implantation” theory. He maintained that during menstruation, and possibly during the interval, uterine contents escape from the abdominal ostia of the tubes, and that in the “spill” are lining cells not only capable of implanting themselves, but also, in suitable soil, of reproducing the menstrual cyclic changes synchronously with the uterine menstrual phases. These implants from the “spill,” Sampson contended, have the power to invade the organ-host upon which they are implanted, and can not only multipty but also, under favorable circumstances, have full functional capacity. These invasions by glandular elements, being closed cavities, menstruate into the cavities each month, causing dilatations into cystic collections varying in size from those of microscopic dimensions to growths as large as a grapefruit. The contents are either liquid blood or blood of tarry consistency, named “tar” or “chocolate” cysts. In 1925 Sampson further demonstrated the possibility of extension of the outgrowths from the endometrium into the submucosal lymphatic channels and blood vessels, into the lumina of which he was able to demonstrate endometrial emboli. Sampson also showed that under abnormal stimuli the mucosa of the fallopian tubes was capable of shedding its epithelium, which, escaping from the fimbriated ends, could implant itself upon contiguous pelvic structures and invade contiguous organs. He also demonstrated that under similar abnormal circumstances the tubal epithelium could invade its own tubal muscular wall, and spread itself in the lymphatics of the mesosalpinx and into other parts of the subjacent broad ligaments.