Cancer research today : chemical and viral carcinogenesis.

London : University of London Audio-Visual Centre, 1974.

1 encoded moving image (39.27 min.) : sound, black and white.

00:39:27

University of London

Unrestricted

CC-BY-NC

Creative Commons Attribution-Non-Commercial 2.0 UK: England & Wales

In English

Presented by Dr A Loveless, Dr P Brookes and Dr I Macpherson. Made by University of London Audio-Visual Centre. Made for British Postgraduate Medical Federation.

This video is one of around 310 titles, originally broadcast on Channel 7 of the ILEA closed-circuit television network, given to Wellcome Trust from the University of London Audio-Visual Centre shortly after it closed in the late 1980s. Although some of these programmes might now seem rather out-dated, they probably represent the largest and most diversified body of medical video produced in any British university at this time, and give a comprehensive and fascinating view of the state of medical and surgical research and practice in the 1970s and 1980s, thus constituting a contemporary medical-historical archive of great interest. The lectures mostly take place in a small and intimate studio setting and are often face-to-face. The lecturers use a wide variety of resources to illustrate their points, including film clips, slides, graphs, animated diagrams, charts and tables as well as 3-dimensional models and display boards with movable pieces. Some of the lecturers are telegenic while some are clearly less comfortable about being recorded; all are experts in their field and show great enthusiasm to share both the latest research and the historical context of their specialist areas.

Segment 1 Loveless describes Ernest Kennaway's research into carcinogenesis. He shows a chemical diagram for nitrogen mustard which is a known chemical carcinogen. Time start: 00:00:00:00 Time end: 00:06:19:00 Length: 00:06:19:00

Segment 2 Loveless shows the chemical diagram of dibenzanthracene and describes its properties. Time start: 00:06:19:00 Time end: 00:10:27:00 Length: 00:04:08:00

Segment 3 Brookes takes over from Loveless. He shows the chemical diagram for acetylamino fluorine and describes its properties. Time start: 00:10:27:00 Time end: 00:17:00:00 Length: 00:06:33:00

Segment 4 Brookes shows the chemical formula of dimethyl nitrosamine and dimethyl sulphate and describes their properties. He then shows the chemical formula for guanine, one of the four constituent bases of DNA. Time start: 00:17:00:00 Time end: 00:23:19:00 Length: 00:06:19:00

Segment 5 Mcpherson takes over from Brookes. He talks about the relationship between DNA and carcinogenesis then shows a diagram which details how normal cells can be transformed to cancerous cells by viruses. Time start: 00:23:19:00 Time end: 00:30:32:00 Length: 00:07:03:00

Segment 6 Mcpherson shows diagrams of the mechanism for cell change by SV40 and Rous sarcoma viruses. Further diagrams are used to ilustrate techniques for finding virus-specific nucleic acid. Time start: 00:30:32:00 Time end: 00:35:41:00 Length: 00:05:09:00

Segment 7 Mcpherson summarises the lecture. Time start: 00:35:41:00 Time end: 00:39:27:01 Length: 00:03:46:00